Obesity and metabolic syndrome

concept
Metabolic syndrome is a condition in which arteriosclerotic diseases such as visceral obesity, insulin resistance / hyperglycemia, abnormal lipid metabolism, rise in blood pressure and the risk of developing type 2 diabetes are accumulated personally. Even if it seemingly does not seem to be an illness or abnormality slightly exceeding the normal value, if it accumulates in an individual, the above risk factor (the risk of cardiovascular disease onset and cardiovascular death is 1.5 to 2 Twice, the risk of developing type 2 diabetes increases 3 to 6 times). Originally it has been proposed as a risk factor other than LDL (bad) cholesterol known as a risk factor for coronary artery disease, so LDL cholesterol is not included in the diagnostic criteria. Hypertension, diabetes, dyslipidemia and obesity are also risk factors for atherosclerotic diseases (eg, about 3 times for diabetes and about 2 times for borderline diabetes mellitus), and these are "slightly abnormal" If you are staying in the treatment area, you need to take more seriously and deal with it.

Symptom
Abdominal girth, blood pressure, etc. can be measured by self, but there is generally no subjective symptom.

Cause
Obesity (especially visceral obesity) is thought to play a central role. Adipocytes are known not only to store fat but also to emit various bad substance. It is also known that obesity not only metabolic syndrome but also many diseases merge.

Inspection for diagnosis
The waist perimeter (abdominal circumference) is 85 cm or more in men and 90 cm or more in females, and it is diagnosed as metabolic syndrome if it falls into two or more of the following three items.

Neutral fat (fasting) 150 mg / dl or more and / or
HDL cholesterol less than 40 mg / dl
Systolic blood pressure of 130 mmHg or more and / or diastolic blood pressure of 85 mmHg or more
Fasting blood glucose 110 mg / dl or more
(In case of drug being treated already, treat it even if it is below the reference value)
Treatment and Prevention
As for metabolic syndrome, obesity plays a central role, so it is important to maintain proper weight in diet therapy, exercise therapy and other life therapy. In addition, smoking cessation is extremely important in preventing arteriosclerosis.
In addition, when it is pointed out at medical examinations etc., there are many cases that it is a merger of hypertension, diabetes (or border type diabetes), dyslipidemia (including high LDLemia) rather than metabolic syndrome. As mentioned above, in this case it is necessary to tackle treatment with further medical knowledge.