Ranitidine is a molecule created in the late '70s by the pharmaceutical company Glaxo as an alternative to competition, belonging to the class of H2 histamine receptor antagonists. The function of ranitidine is to block the secretion of hydrochloric acid in the stomach caused by the intake of foods containing substances like caffeine, and by the increase in the level of insulin, acting directly on the H2 histamine receptors.
what is ranitidine
Through the action of ranitidine , there will be a reduction in the volume of secreted gastric juice and a reduction in pepsin, the amount of which depends on the volume of gastric juice. In addition, ranitidine also offers a protective action on the gastric mucosa counteracting the irritant effects of NSAIDs. The action of ranitidine does not promote the release of hormones produced by histamine because its hydrophilic nature does not allow it to overcome the blood-brain barrier in large quantities.
ALL THE USES OF RANITIDINE
The use of the drug is recommended for those who experience stomacal problems , such as gastric and duodenal ulcer, gastroesophageal reflux and Zollinger-Ellison syndrome. The treatments for these diseases involve the administration of the drug in limited and precise quantities according to the type of problem, taking it with a little water during the evening hours. For example, a single administration of 300mg is recommended to treat a gastric ulcer. of ranitidine mixed with a little water or milk, on a full stomach, before going to bed.
SIDE EFFECTS AND CONTRAINDICATIONS
Clearly, like any drug, it can have side effects such as diarrhea and other gastrointestinal complications, changes in liver values, headaches, rashes, fatigue and, rarely, tachycardia.
The use of ranitidine should be monitored and targeted for the resolution of that specific problem. First of all, before the assumption, it is necessary to ensure the absence of a possible gastric carcinoma, as ranitidine, alleviating the symptoms, can make the correct diagnosis of the neoplasia complicated. In the case of renal failure it is advisable to take minimum doses of renitidine or to administer the same in a longer time. The same applies in case of liver failure.
Care should be taken when ranitidine is administered simultaneously with oral anticoagulants, as there is a risk that the effect of anticoagulants will increase. The same goes for nifedipine. However, in order to have greater peace of mind and security, it will be useful to perform a test related to myocardial activity at regular intervals. If you are taking ranitidine and morphine at the same time, you may experience negative effects characterized by mental confusion.
Being a not very aggressive drug, ranitidine is well assimilated by our body. Side effects are more related to gastrointestinal complications, such as nausea, vomiting and abdominal pain. Some studies have shown that interrupting the administration of ranitidine can cause acid hypersecretion. Other negative effects that can usually occur are headache, drowsiness and dizziness and, in rare cases, disorientation and agitation. If ranitidine is given intravenously there is a risk of slight bradycardia.
what is ranitidine
Through the action of ranitidine , there will be a reduction in the volume of secreted gastric juice and a reduction in pepsin, the amount of which depends on the volume of gastric juice. In addition, ranitidine also offers a protective action on the gastric mucosa counteracting the irritant effects of NSAIDs. The action of ranitidine does not promote the release of hormones produced by histamine because its hydrophilic nature does not allow it to overcome the blood-brain barrier in large quantities.
ALL THE USES OF RANITIDINE
The use of the drug is recommended for those who experience stomacal problems , such as gastric and duodenal ulcer, gastroesophageal reflux and Zollinger-Ellison syndrome. The treatments for these diseases involve the administration of the drug in limited and precise quantities according to the type of problem, taking it with a little water during the evening hours. For example, a single administration of 300mg is recommended to treat a gastric ulcer. of ranitidine mixed with a little water or milk, on a full stomach, before going to bed.
SIDE EFFECTS AND CONTRAINDICATIONS
Clearly, like any drug, it can have side effects such as diarrhea and other gastrointestinal complications, changes in liver values, headaches, rashes, fatigue and, rarely, tachycardia.
The use of ranitidine should be monitored and targeted for the resolution of that specific problem. First of all, before the assumption, it is necessary to ensure the absence of a possible gastric carcinoma, as ranitidine, alleviating the symptoms, can make the correct diagnosis of the neoplasia complicated. In the case of renal failure it is advisable to take minimum doses of renitidine or to administer the same in a longer time. The same applies in case of liver failure.
Care should be taken when ranitidine is administered simultaneously with oral anticoagulants, as there is a risk that the effect of anticoagulants will increase. The same goes for nifedipine. However, in order to have greater peace of mind and security, it will be useful to perform a test related to myocardial activity at regular intervals. If you are taking ranitidine and morphine at the same time, you may experience negative effects characterized by mental confusion.
Being a not very aggressive drug, ranitidine is well assimilated by our body. Side effects are more related to gastrointestinal complications, such as nausea, vomiting and abdominal pain. Some studies have shown that interrupting the administration of ranitidine can cause acid hypersecretion. Other negative effects that can usually occur are headache, drowsiness and dizziness and, in rare cases, disorientation and agitation. If ranitidine is given intravenously there is a risk of slight bradycardia.
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